Indications - Cancer

1. Hydrogen Reduces Oxidative Stress

Reactive Oxygen Species(ROS) are found in abundance in cancer cells. ROS create oxidative stress which is well known to be a cause of a wide range of diseases including cancer. ROS are involved in both the initiation and progression of cancer. ROS causes oxidative DNA and protein damage, as well as damage to tumor suppressor genes. Studies show that Hydrogen is a “potent antioxidant and exhibits anti-inflammatory and potentially anticancer-like activities”. 

2. Hydrogen Protects DNA

Oxidative stress damages cellular DNA which leads to mutations. ROS cause oxidative DNA and protein damage as well as damage to tumour suppressor genes. Unlike other antioxidants which are larger, the tiny size of H2 molecules allows them to penetrate bio membranes and diffuse into the mitochondria and nuclei thereby protecting the nuclear DNA and mitochondria.

3.Hydrogen Suppresses Genetic Mutations

Somatic mutations are genetic alterations that affect all of the cells that descend from mutated cells. These mutations are often caused by environmental factors such as ultraviolet radiation exposure and chemicals. The mutations give rise to various diseases including cancer. Hydrogen has a beneficial effect on cancer development by suppressing mutations.

4. Hydrogen Suppresses Cancer Cell Growth

Hydrogen suppresses angiogenesis the development of blood vessels in tumours. By suppressing angiogenesis, Hydrogen denies the tumour the ability to feed and grow. Hydrogen inhibits tumour growth by reducing oxidation products. Hydrogen inhibits massive cancer cell growth indicative of early-stage cancer. Hydrogen scavenges ROS maintaining antioxidative potential both inside and outside cells inhibiting cancer growth. Studies indicate that while Hydrogen inhibits cancer cell growth, it does not inhibit healthy cell growth.

5. Hydrogen Induces Cancer Cell Death

Apoptosis is natural or programmed cell death, it is a natural part of the life cycle of cells. Apoptosis is preferred to necrosis, which is the unnatural death of cells typically induced by infection, toxins, and trauma which can lead to tumour growth. Studies show that Hydrogen induces cancer cell apoptosis thereby enhancing anticancer activity. Studies also show that Hydrogen inhalation induces apoptosis in human leukaemia cells and affected neurons, but Hydrogen does not increase cell death in healthy cells.

6. Hydrogen Suppresses The Spread of Cancer

Metastasis is a term to describe the ability of cells to invade tissue and establish secondary tumours in remote sites and is the main cause of cancer-related death in humans. ROS are involved in metastatic processes including invasion of cancer cells into the surrounding primary tumour sites. Studies show that Hydrogen may be a therapeutic agent in cancer prevention and metastasis through its anti-ROS effects. MMP’s Matrix Metalloproteinase, are proteins that facilitate biological reactions. Studies note that MMP’s are up-regulated in the course of various malignancies of the breast, colon, pancreas, and liver. MMP’s are viewed as tumour markers and have found to be predictive in metastasis in breast cancer patients. Increased expression of MMP in a primary breast tumour is associated with aggressive disease and unfavourable outcomes. Studies show that Hydrogen down-regulates the gene expression of MMP’s.

7. Hydrogen Helps Anti-Cancer Drugs

Anti-tumour agents are typically cytotoxic drugs that damage healthy tissue and organs while targeting cancer cells. For example, one study showed that 40% of patients receiving chemotherapy agents suffered liver damage. Increased levels of ROS play a role in the side effects. A highly respected review paper states: “Hydrogen has emerged as a promising cancer remedy as a preventative agent or in combined therapy with anticancer drugs. Hydrogen inhalation might mitigate the side effects of anticancer drugs by decreasing oxidative stress and ameliorating metamorphosis due to decreased apoptosis in healthy cells”. Another study states: “Due to its safety, efficacy, and convenience, hydrogen should be considered as a potential therapy for heart and liver injury caused by doxorubicin a chemotherapy drug. In the study, Hydrogen did not impair the anti-tumour effect of the drug.

8. Hydrogen Protects From Radiation Therapy

Nearly half of newly diagnosed cancer patients receive radiotherapy. While radiotherapy destroys malignant cells, it also affects normal surrounding cells. Acute radiotherapy side effects include fatigue, nausea, diarrhea, dry mouth, loss of appetite, hair loss, sore skin, and depression. The side effects are associated with increased oxidative stress and inflammation due to the generation of ROS during radiotherapy. The success of radiotherapy is limited by the toxicity of healthy cells in the surrounding tissue. In fact, radiation itself can induce many types of cancer, especially leukaemia and lymphoma. An animal study found that Hydrogen protected mice from radiation-induced thymic lymphoma. Another animal study showed that Hydrogen reduced radiation-induced lung damage in mice in the early stage cancer and lung fibrosis in later stage cancer. Yet another animal study showed that Hydrogen protected the gastrointestinal tract of mice from radiation. A review paper stated that: “our findings suggested that hydrogen may be used as a potential therapeutic to alleviate intestinal injury induced by radiotherapy for abdominal and pelvic cancer in preclinical settings”. Radiotherapy adversely affects 95% of patients and a study found that hydrogen significantly reduced the severity of dermatitis caused by radiation. Another study indicates that Hydrogen helps the immune system placed under duress by radiotherapy 

9. Hydrogen Improves the QOL Scores

Cancer patients receiving chemotherapy or radiotherapy or a combination of both often experience varying degrees of QOL. Studies show that QOL scores during radiotherapy were significantly improved in patients treated with hydrogen therapy. Other studies indicate that “oral administration of hydrogen-rich water may reduce organ toxicity induced by chemotherapy, improve QOL, and decelerate weight loss without affecting the effectiveness of chemotherapy.

10. Hydrogen Increases Survival Rates of Cancer Patients

The first hydrogen study that captured the interest of the scientific community was published in 2007. As such, studies on the effects of survival rates are limited to animal studies at this time. A study shows that Hydrogen improved the survival of mice with colon cancer who were being tested for chemotherapy. Another study showed the increased survival rates of mice receiving Hydrogen, 30 weeks after receiving radiation. Another study shows that survival rate and weight loss in mice was improved after receiving chemotherapy when the mice received Hydrogen therapy. Another study concluded that Hydrogen is “safe, easy to administer, and cost-effective, protects against radiation-induced death”. Long term human studies need to be completed to verify the findings of the improved survival rates of mice after receiving Hydrogen therapy, but the animal studies provide grounds for considerable optimism about the therapeutic benefits of Hydrogen.

Clinical studies:

( Kindly ask us for PDF format of the below researched clinical papers. We will be glad to send them by mail or by whatsapp ) 

1) Anti‐inflammatory and antitumor action of hydrogen via reactive oxygen species

2) Hydrogen Gas in Cancer Treatment – Frontiers in Oncology 

3) Brain Metastases Completely Disappear in Non-Small Cell Lung Cancer Using Hydrogen Gas Inhalation: A Case Report 

4) Therapeutic potential of molecular hydrogen in ovarian cancer

5) Hydrogen as a New Class of Radioprotective Agent

6) Hydrogen as a Tool in the Fight to Reduce Cancer treatment side effects.

7) Hydrogen inhalation alleviates side effects of chemotherapies.

8) Hydrogen gas emerges as another GSM ( Gas signalling molecule) potential in cancer treatment. 

9) Hydrogen as a Tool in the Fight to Reduce Cancer side effects, protective and anti cancer.

 

Effective | Non Invasive | Drugless | Safe

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